My research focuses on activating the tumor-suppressor role of the RNF43 protein, to prevent cells over-growth. We are developing and optimizing peptide-based anti-cancer lead compounds that targets RNF43.
I use biophysical methods to study the protein- protein interactions of cancer related proteins.
I specifically focus on the ASPP protein family and the NAF-1 protein.
I am developing anti-cancer compounds based on the molecular understanding of the interactions of the STIL protein with itself, and with its partner proteins.
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