Our research focus is mainly on the interactions of cancer and apoptosis-related proteins, many of them contain disordered regions. These include for example:

• The apoptosis-regulating ASPP protein family (Katz C. et al., PNAS, 2008; Rotem S. et al., J. Biol. Chem., 2008; Iosub-Amir A. et al., MedChemComm, 2014; Iosub-Amir et al., Sci. Rep., 2015; Iosub-Amir et al., Chem. Sci., 2019; Mayer G. et al., Chem. Eur. J., 2020)
  (Iosub-Amir et al., 2015)
   
• The centrosomal STIL protein, which is upregulated in cancer (Amartely H. et al., ChemComm, 2013; Amartely H. et al., Chem. Sci., 2016; David A. et al., Sci. Rep., 2016)
  
• Proteins involved in the Wnt signalling pathway, including Axin and APC (Garfagnini T. et al., Biophys. J., 2021)
  (Garfagnini et al., 2021)
   
• The Naf-1 protein (Tamir S. et al., PNAS, 2014; Iosub-Amir A. et al., Chem. Sci., 2019)
  (Iosub-Amir et al., 2019)